Dennis E Ohman Selected Research

Alginates

5/2015	Dimeric c-di-GMP is required for post-translational regulation of alginate production in Pseudomonas aeruginosa.
1/2015	Cell wall stress activates expression of a novel stress response facilitator (SrfA) under σ22 (AlgT/U) control in Pseudomonas aeruginosa.
8/2014	P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation.
8/2013	Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation.
1/2012	Identification of genes in the σ²² regulon of Pseudomonas aeruginosa required for cell envelope homeostasis in either the planktonic or the sessile mode of growth.
6/2008	Membrane topology and roles of Pseudomonas aeruginosa Alg8 and Alg44 in alginate polymerization.
11/2005	Adaptations of Pseudomonas aeruginosa to the cystic fibrosis lung environment can include deregulation of zwf, encoding glucose-6-phosphate dehydrogenase.
10/2005	Role of an alginate lyase for alginate transport in mucoid Pseudomonas aeruginosa.
7/2005	Epimerase active domain of Pseudomonas aeruginosa AlgG, a protein that contains a right-handed beta-helix.
2/2003	The dual roles of AlgG in C-5-epimerization and secretion of alginate polymers in Pseudomonas aeruginosa.

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Dennis E Ohman Research Topics

Disease

11	Cystic Fibrosis (Mucoviscidosis) 01/2019 - 06/2002
10	Infections 01/2019 - 11/2002
4	Lung Diseases (Lung Disease) 06/2008 - 11/2002
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2019 - 01/2015
2	Keratitis 02/2012 - 05/2004
1	Acne Vulgaris 01/2017
1	Persistent Infection 08/2014
1	Acquired Immunodeficiency Syndrome (AIDS) 08/2013
1	Edema (Dropsy) 02/2012
1	Inflammation (Inflammations) 02/2012
1	Abscess 02/2012
1	Endophthalmitis (Ophthalmia) 07/2009
1	Suppuration 03/2006

Drug/Important Bio-Agent (IBA)

12	AlginatesIBA 05/2015 - 06/2002
3	Polysaccharides (Glycans)IBA 10/2005 - 06/2002
2	Sigma FactorIBA 01/2019 - 11/2002
2	staphylolysinIBA 02/2012 - 07/2009
2	Methicillin (Metin)FDA Link 02/2012 - 05/2004
2	Peptide Hydrolases (Proteases)FDA Link 07/2009 - 05/2004
2	lipid-associated sialic acid (LASA)IBA 07/2009 - 05/2004
2	Capsules (Microcapsules)IBA 10/2005 - 07/2005
1	NitritesIBA 01/2019
1	Antimicrobial PeptidesIBA 01/2017
1	Adenosine Monophosphate (AMP)IBA 01/2017
1	PolymersIBA 08/2013
1	Bovine Serum AlbuminIBA 02/2012
1	Therapeutic UsesIBA 02/2012
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2012
1	polytetramethylene glycolIBA 03/2006
1	5,5-dimethylhydantoinIBA 03/2006
1	isophorone diisocyanateIBA 03/2006
1	Polyurethanes (Polyurethane)IBA 03/2006
1	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 11/2005
1	LysostaphinIBA 05/2004
1	Vancomycin FDA LinkGeneric 05/2004
1	Virulence Factors (Pathogenicity Factors)IBA 11/2002
1	LipopolysaccharidesIBA 11/2002

Therapy/Procedure

1	Injections 02/2012
1	Intravitreal Injections 07/2009
1	Therapeutics 07/2009